Download Our Application Paper
An Image-Based Method to Detect and Quantify T Cell Mediated Cytotoxicity of 2D and 3D Target Cell Models

 

Download our application paper to discover how our CD3 T cells were used in the following analysis. 18-0023_ApplicationPaper_Tcel_CMC

T cell mediated cytotoxicity, which plays an important role in immunotherapy, is imaged and quantified using sensitive in vitro methods.

  • A 3D tumoroid target cell model was used to generate extended incubation studies
  • Cytotoxicity was quantified using a live cell fluorescent necrosis probe
  • Kinetic imaging measured 2D and 3D target cell necrotic induction 


 

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