Download our application paper to discover how our CD3 T cells were used in the following analysis.
T cell mediated cytotoxicity, which plays an important role in immunotherapy, is imaged and quantified using sensitive in vitro methods.
- A 3D tumoroid target cell model was used to generate extended incubation studies
- Cytotoxicity was quantified using a live cell fluorescent necrosis probe
- Kinetic imaging measured 2D and 3D target cell necrotic induction