Drug discovery programs frequently benefit by evaluating compounds in a stable, in vivo-relevant, long-term
hepatic model. Compared to conventional suspension or plated hepatocyte models, long-term systems can provide important metabolism and toxicity data, especially for low-turnover compounds.
This webinar will provide an overview of the HEPATOPAC® system, a micropatterned hepatocyte-fibroblast co-culture that remains viable for several weeks. HEPATOPAC study design methods and data have been extensively published in peer-reviewed journals, as these cultures are used to address unique research problems.
BioIVT’s contract research services group offers the HEPATOPAC model for sponsored studies to investigate metabolic stability, metabolism identification and predictive and mechanistic hepatotoxicity.
Attend our webinar to learn how we tailor studies to meet your program’s unique requirements. We’ll discuss all the elements of study design protocols, including:
- Considerations for plate format
- Multi-species and multi-donor plates
- Milestones
- Final reports